He had presented a letter from 12 governments calling for more deregulation to boost economic growth
Separately all EU states, apart from the UK and the Czech Republic, have signed a new fiscal treaty aimed at enforcing budget discipline in the eurozone.
BBC political correspondent Iain Watson said Mr Cameron’s complaint at a leaders’ dinner to open the summit was “five minutes of frustration”.
Government sources said Mr Cameron wanted to fire a shot across the bows of Brussels bureaucrats.
During a speech in January at the World Economic Forum in Davos Cameron said the Coalition Government was pursuing an unashamedly, pro-business agenda, which involved scrapping needless red tape, simplifying planning and reviewing all regulation.
He said there was a need for bold action at a European level, with Europe’s lack of competitiveness remaining its Achilles Heel.